{"id":11699,"date":"2021-11-17T12:30:41","date_gmt":"2021-11-17T11:30:41","guid":{"rendered":"https:\/\/athleatcoach.com\/caffeine-does-the-effect-decrease-with-continuous-intake\/"},"modified":"2026-04-28T23:25:25","modified_gmt":"2026-04-28T21:25:25","slug":"caffeine-does-the-effect-decrease-with-continuous-intake","status":"publish","type":"knowledge_base","link":"https:\/\/athleatcoach.com\/en\/knowledge_base\/caffeine-does-the-effect-decrease-with-continuous-intake\/","title":{"rendered":"Caffeine: Does the Effect Decrease with Continuous Intake?"},"content":{"rendered":"<h2><strong>Mechanism of Action of Caffeine<\/strong><\/h2>\n<p>One of the main mechanisms by which caffeine exerts its performance-enhancing effect is by docking to adenosine receptors. This not only counteracts fatigue, but we also experience less pain (<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33388079\/\">1<\/a>). <\/p>\n<p>&nbsp;<\/p>\n<p><img decoding=\"async\" class=\"alignnone size-large wp-image-7983\" src=\"https:\/\/athleatcoach.com\/wp-content\/uploads\/2021\/05\/koffein-wirkmechanismus-1024x576.png\" alt=\"\" width=\"1024\" height=\"576\" srcset=\"https:\/\/athleatcoach.com\/wp-content\/uploads\/2021\/05\/koffein-wirkmechanismus-980x551.png 980w, https:\/\/athleatcoach.com\/wp-content\/uploads\/2021\/05\/koffein-wirkmechanismus-480x270.png 480w\" sizes=\"(min-width: 0px) and (max-width: 480px) 480px, (min-width: 481px) and (max-width: 980px) 980px, (min-width: 981px) 1024px, 100vw\" \/><\/p>\n<h2><strong>Theory of the Habituation Effect <\/strong><\/h2>\n<p>At least in animal studies, continuous caffeine intake has led to an increased concentration of adenosine receptors (<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/8242688\/\">2<\/a>), which, at least in theory, should reduce the effectiveness with the same caffeine intake.<\/p>\n<p>But can this observed effect also be transferred to humans and, above all, to athletic performance?<\/p>\n<h2><\/h2>\n<h2><strong>Performance Studies with and without Coffee Drinkers<\/strong><\/h2>\n<p>In an elegant study design, Beaumont et al., 2017 investigated whether regular coffee consumption affects the effectiveness of caffeine (<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/27762662\/\">3<\/a>)?<\/p>\n<blockquote>\n<h3>What Makes this Study so Special?<\/h3>\n<\/blockquote>\n<p>Compared to other studies, the subjects were not simply divided into a group with high or low caffeine consumption based on their current coffee consumption, but the participants all performed the performance test once with and without caffeine intake in a cross-over design. After that, half of the athletes consumed 3 mg of caffeine per kg of body weight daily for 3 weeks, the other half a low-dose carbohydrate capsule as a placebo. <\/p>\n<p><img decoding=\"async\" class=\" wp-image-8491 aligncenter\" src=\"https:\/\/athleatcoach.com\/wp-content\/uploads\/2021\/11\/studiendesign.png\" alt=\"\" width=\"817\" height=\"260\" srcset=\"https:\/\/athleatcoach.com\/wp-content\/uploads\/2021\/11\/studiendesign.png 817w, https:\/\/athleatcoach.com\/wp-content\/uploads\/2021\/11\/studiendesign-480x153.png 480w\" sizes=\"(min-width: 0px) and (max-width: 480px) 480px, (min-width: 481px) 817px, 100vw\" \/><\/p>\n<p>After 3 weeks, the same performance test was then repeated with acute caffeine intake: 30 min on the bicycle ergometer, during which the performance was measured (<em>total kJ<\/em>).<\/p>\n<h3><\/h3>\n<h3><strong>The Result?<\/strong><\/h3>\n<p>In the first performance test, both groups were able to increase their performance. In the placebo group, the performance increase could be repeated after 3 weeks. While the performance of the athletes who had consumed caffeine for 3 weeks in the meantime, a decrease in the measured work (<em>kJ<\/em>) decreased by 7.3%.  <\/p>\n<h2><\/h2>\n<p>&nbsp;<\/p>\n<h2><strong>One Study Alone is not Enough<\/strong><\/h2>\n<p>However, there are also studies that have found the opposite (<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/1893906\/\">4<\/a>, <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28495846\/\">5<\/a>, <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/12235019\/\">6<\/a>).<\/p>\n<p>In an older study (<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/1893906\/\">4<\/a>), 17 subjects were divided into two groups: non-coffee drinkers and consumers of more than 300 mg of caffeine daily. No differences were found between the two groups in a &#8220;time-to-exhaustion test.&#8221; This observation, in turn, supported the thesis that continuous caffeine intake has no negative effect.  <\/p>\n<p>Gon\u00e7alves et al. (<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28495846\/\">5<\/a>) divided 40 trained cyclists into 3 groups with low daily caffeine consumption (average = 58 mg per day), moderate consumption (average = 143 mg per day) and high caffeine consumption (average = 351 mg per day).<\/p>\n<p>In a 30-minute &#8220;time-trial&#8221; test on the bicycle, all 3 groups showed improved performance compared to a placebo group, and more importantly for our question of the possible habituation effect, there were no differences in performance between people with low and high daily caffeine consumption.<\/p>\n<p>&nbsp;<\/p>\n<p><img decoding=\"async\" class=\"size-full wp-image-8495 aligncenter\" src=\"https:\/\/athleatcoach.com\/wp-content\/uploads\/2021\/11\/low-moderate-high-caffeine-cinsumption-peformance-gonzales.png\" alt=\"\" width=\"578\" height=\"440\" srcset=\"https:\/\/athleatcoach.com\/wp-content\/uploads\/2021\/11\/low-moderate-high-caffeine-cinsumption-peformance-gonzales.png 578w, https:\/\/athleatcoach.com\/wp-content\/uploads\/2021\/11\/low-moderate-high-caffeine-cinsumption-peformance-gonzales-480x365.png 480w\" sizes=\"(min-width: 0px) and (max-width: 480px) 480px, (min-width: 481px) 578px, 100vw\" \/><\/p>\n<p>&nbsp;<\/p>\n<p>Overall, the results are unfortunately not clear and further high-quality studies are needed to answer the question of a possible habituation effect.<\/p>\n<blockquote>\n<h2>But how should We Use Caffeine with our Athletes in the Meantime?<\/h2>\n<\/blockquote>\n<h2><\/h2>\n<p>&nbsp;<\/p>\n<h2><strong>Does a Short-Term Withdrawal Help?<\/strong><\/h2>\n<p>Here we can say with greater certainty that short breaks in caffeine intake do not help: because the two studies known to us have not been able to find any differences in performance with a withdrawal of 2-4 days (<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/9760346\/\">7<\/a>, <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/21279864\/\">8<\/a>).<\/p>\n<p>&nbsp;<\/p>\n<h2><strong>Our Interpretation of the Data<\/strong><\/h2>\n<p>We cannot currently answer the question of a potential habituation effect clearly with YES or NO.<\/p>\n<p>The decrease in performance is at least possible. But the effect &#8211; if it exists &#8211; will probably be very low with low daily caffeine consumption (see studies (<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/1893906\/\">4<\/a>, <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28495846\/\">5<\/a>, <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/12235019\/\">6<\/a>). <\/p>\n<p>We therefore do not &#8220;forbid&#8221; our athletes from consuming coffee daily! Also, because it is an important ritual for many and contributes to socializing. <\/p>\n<p>What we do, however, is limit the daily intake purely for enjoyment to 1 large cup of coffee. And we use caffeine as a supplement very specifically, and not before every training session, but only before &#8220;key sessions&#8221;, or when the athlete feels very tired. In the end, however, we always discuss the &#8220;caffeine strategies&#8221; and adapt them individually to the situation of each person.  <\/p>\n<p>&nbsp;<\/p>\n<h2>Did you like the article? Then do us a favor and share the information with other athletes and coaches. <\/h2>\n<p>&nbsp;<\/p>\n<h3>THANK YOU &#8211; your Team Athl<strong>EAT<\/strong>Coach<\/h3>\n<p>&nbsp;<\/p>\n","protected":false},"author":5,"featured_media":11700,"menu_order":0,"template":"","format":"standard","meta":{"_acf_changed":false,"_et_pb_use_builder":"","_et_pb_old_content":"","_et_gb_content_width":""},"free-resources":[418],"product":[],"audience":[360,359],"class_list":["post-11699","knowledge_base","type-knowledge_base","status-publish","format-standard","has-post-thumbnail","hentry","free-resources-supplements","audience-athlete","audience-coach"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.7 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Caffeine: Does the Effect Decrease with Continuous Intake? - athlEATcoach | Sports Nutrition<\/title>\n<meta name=\"description\" content=\"How does caffeine improve your athletic performance? 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